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When antibodies mislead: the quest for validation

Research antibodies don’t always do what it says on the tin. Test for true signals before you start your experiment.
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  1. Monya Baker
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Commercial antibodies are commonplace in biology laboratories. Researchers use these giant Y-shaped proteins to detect specific molecules in cells, tissues and test tubes. But sometimes the proteins detect other molecules, too — or even instead. When that happens, confusion can snowball.

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Nature 585, 313-314 (2020)

doi: https://doi.org/10.1038/d41586-020-02549-1

References

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