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Stem-cell therapies use immune system to repair broken hearts

Study in mice shows that a chemical can also improve the organs’ performance.
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  1. David Cyranoski

    1. David Cyranoski reports for Nature from Shanghai, China.

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Biologists have uncovered the mechanism by which stem-cell therapies improve heart function. Working in mice, a team of researchers found that the cells prompt an immune response that improves the organ’s function and also discovered how to mimic this repair with a chemical.

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doi: https://doi.org/10.1038/d41586-019-03645-7

References

  1. Vagnozzi, R. J. et al. Nature https://doi.org/10.1038/s41586-019-1802-2 (2019).

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  2. Epstein, J. JAMA Cardiol. 4, 95–96 (2018).

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  3. Liu, Y. et al. Nat Biotechnol 36, 597–605 (2018).

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